Biovorin 15 mg (Leucovorin Calcium) 20 tab

Biovorin 15 is a calcium folinate preparation used in oncology to enhance the effect of chemotherapeutic drugs and protect healthy cells.

Basic Drug Information

• International Name: Calcium Leucovorin
• Manufacturer: [Specify manufacturer]
• Dosage Form: Tablets 15 mg
• Package Quantity: 20 tablets
• Shelf Life: [Specify expiration date]
• Storage Conditions: Store at 15°C to 25°C

Indications for Use

• In Oncology:
  • Enhancement of therapeutic effect of fluoropyrimidines
  • Antidote for overdose of folic acid antagonists
  • Combined chemotherapy of various cancers
• Other Uses:
  • Treatment of megaloblastic anemia
  • Correction of folic acid deficiency

Administration and Dosage

Standard Dosage:

• For Chemotherapy Enhancement: 15-30 mg every 6-8 hours
• As Antidote: up to 75 mg within 12-24 hours
• Maintenance Therapy: 15 mg daily

Administration Features:

• Take orally with water
• Strictly adhere to timing relative to chemotherapy
• Dosage adjusted individually by physician

Contraindications

• Hypersensitivity to drug components
• Pernicious anemia
• Severe renal impairment
• Pregnancy and lactation (only under strict indications)

Side Effects

Common:

• Nausea, vomiting
• Diarrhea or constipation
• Skin allergic reactions
• Dizziness

Rare:

• Bronchospasm
• Anaphylactic reactions
• Sleep disorders

Precautions

• Regular blood count monitoring
• Kidney and liver function monitoring
• Caution when taking with other drugs

Drug Interactions

• Enhances effect of fluorouracil
• May interact with barbiturates, anticonvulsants
• Incompatible with high-dose methotrexate

Manufacturer: Zodus (India)