Pirfenex 200mg 30 tablets

🎯 Indication

Pirfenex 200mg is indicated for the treatment of idiopathic pulmonary fibrosis (IPF) in adults.

• It does not cure the disease but helps slow the decline in lung function and reduces the rate of scar tissue formation.
• The drug has anti-inflammatory and anti-fibrotic properties.

💊 Dosage and Administration

The medication must be taken strictly as prescribed by a physician. The standard regimen involves a gradual dose escalation to improve tolerability.

• Initial dose: 200 mg (1 tablet) three times a day.
• Dose titration: The dose is increased by 200 mg per intake each week until the maintenance dose is reached.
• Maintenance dose: 600 mg (3 tablets) three times a day (total daily dose of 1800 mg).
• Important: Take with or after food, as taking it on an empty stomach increases blood concentration and the risk of side effects.

⚠️ Common Side Effects

The most common side effects include:

• Gastrointestinal: Nausea, vomiting, diarrhea, loss of appetite, weight loss.
• Skin: Rash, severe photosensitivity (reaction to sunlight and UV exposure).
• Nervous system: Headache, dizziness, drowsiness, insomnia.
• Liver: Elevated liver enzymes (ALT, AST). Regular monitoring of liver function is required.

🚫 Contraindications

This medication is contraindicated in the following cases:

• Allergy to pirfenidone or any component of the formulation.
• Severe liver or kidney impairment (including patients on dialysis).
• Pregnancy and breastfeeding.
• Concomitant use of fluvoxamine (an antidepressant).

⚠️ Important Precautions

1. Photosensitivity: Avoid prolonged sun exposure during treatment. Use high-protection sunscreen and wear protective clothing to reduce the risk of severe sunburn.
2. Liver Function Monitoring: Regular blood tests are essential to monitor liver enzymes throughout the treatment.
3. Driving and Machinery: The medication can cause dizziness and significant drowsiness. Caution is advised when driving or operating machinery.
4. Smoking: Smoking reduces the effectiveness of pirfenidone. It is recommended to quit smoking during treatment.
5. Drug Interactions: Inform your doctor about all medications you are taking, especially antibiotics (ciprofloxacin) and medications for heartburn (omeprazole), as they may affect how Pirfenex works.

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