MOHRUS TAPE L 40 mg: Transdermal Ketoprofen Patch for Joint and Muscle Pain

MOHRUS TAPE L is a modern transdermal patch impregnated with the non-steroidal anti-inflammatory drug (NSAID) ketoprofen at a dose of 40 mg per unit. A pack of 70 patches is designed for a long-term therapeutic course and is popular among patients with chronic joint and spinal conditions, as well as athletes seeking localized pain relief without systemic burden on the body.

🧠 How It Works: Transdermal Delivery for Targeted Anti-Inflammatory Action

The key advantage of MOHRUS TAPE L over oral NSAID formulations lies in its active-substance delivery method. Ketoprofen, penetrating the skin directly to the pain source, builds a therapeutic concentration precisely within the target zone — the affected joint, inflamed muscle, or injured ligament. Meanwhile, the concentration of the drug in the systemic bloodstream remains minimal. This yields two important consequences:

• High Local Efficacy. The active ingredient concentrates where it is actually needed, rather than dispersing throughout the entire body.
• Reduced Systemic Risks. The irritant effect on the gastric mucosa and the toxic burden on the liver — classic problems of long-term oral NSAID therapy — are minimized.

Ketoprofen, belonging to the propionic acid derivative group, inhibits the activity of cyclooxygenase (COX-1 and COX-2), interrupting the cascade of prostaglandin synthesis — the mediators of inflammation, pain, and fever. The result: edema reduction, pain relief, and restoration of mobility in the affected region.

📋 Indications: When a Doctor Prescribes MOHRUS TAPE L

The drug is recommended for local symptomatic treatment in the following conditions:

• Joint Pain. Osteoarthritis of the knee, hip, and shoulder joints; rheumatoid arthritis; gouty arthritis in the subacute and chronic phases.
• Inflammatory Processes in Soft Tissues. Myositis, tendonitis, tenosynovitis, bursitis, periarthritis, fasciitis.
• Vertebrogenic Pain. Dorsalgia, lumbago, sciatica, radiculopathy, pain in the cervical and thoracic spine.
• Sports Injuries. Ligament sprains, bruises, hematomas, post-traumatic soft tissue edema.

💊 Directions for Use: How to Apply the Patch Correctly

• Skin Preparation. The patch is applied exclusively to clean, dry, and intact skin. The application site must be free of wounds, abrasions, burns, dermatological rashes, or signs of infection.
• Placement. The patch is positioned directly over the area of maximum pain.
• Wear Duration. The standard recommendation is one patch for 24 hours. After one day, it is replaced with a new one.
• Maximum Daily Dosage. Up to 3–4 patches may be used per day, depending on the physician's recommendations and the surface area of the affected zone.
• Course Duration. The length of therapy is determined by the doctor. If no improvement is observed within the recommended period, a repeat consultation is necessary.

⚠️ Contraindications: Who Should Not Use This Product

Absolute prohibitions for MOHRUS TAPE L use:

• Hypersensitivity to ketoprofen, other NSAIDs (including acetylsalicylic acid), or any auxiliary component of the patch.
• History of Allergic Reactions to NSAIDs. If bronchospasm, urticaria, or angioedema previously occurred while taking aspirin or ibuprofen.
• Damaged Skin at the intended application site: weeping dermatitis, eczema, infected abrasions, open wounds.
• Pregnancy (Third Trimester) and Lactation. In the first and second trimesters — only after a thorough physician-led benefit-risk assessment. In the third trimester, ketoprofen, like other NSAIDs, is contraindicated due to the risk of premature closure of the fetal ductus arteriosus and suppression of labor.
• Pediatric Use (safety and efficacy in children have not been established).

📊 Potential Adverse Reactions

Most side effects are confined to the application site:

• Common: Mild redness, transient itching, a sensation of warmth or burning under the patch.
• Rare: Pronounced contact dermatitis, vesicular rashes, photosensitization (increased skin sensitivity to ultraviolet light at the patch site).
• Very Rare Systemic Reactions: Headache, dyspeptic phenomena (nausea, epigastric discomfort) — possible when using a large number of patches simultaneously or when the skin barrier integrity is compromised.

If persistent irritation develops, the rash spreads beyond the application zone, or systemic symptoms appear, the patch should be removed and a physician consulted.

🛡️ Special Instructions and Drug Interactions

• Avoid combined use with other NSAIDs (oral, rectal, injectable) without medical approval. The additive effect elevates the risk of systemic complications, including gastrointestinal bleeding and nephrotoxicity.
• Sun Protection. After patch removal, the treated skin area should not be exposed to direct sunlight or tanning beds for a minimum of 12 hours — this reduces the risk of photosensitization.
• Do Not Occlude. Do not apply airtight dressings over the patch.
• Before starting the course, always read the complete official manufacturer's instructions carefully.

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